DES (diethylstilbestrol) dosage advice

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Cara.M's picture
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Joined: 2013-01-11

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I haven't been here for a while -- managing my two pups and my job is about all I seem to have time for.

Fidget (my shelter adopted likely 100% dobie) is now probably about 7 years old.  She has "leaked," probably due to spay incontinence, since we got her - it's likely why she was in the shelter.  She's been on proin, but its effectiveness has decreased somewhat, over time, so our veterinary office's relatively new vet suggested we try DES for her.  

We started yesterday morning on one 1mg pill - 1 per day for 5-7 days, then we start to back off to see what her dosage is.  We took her COMPLETELY off the Proin, when we started the DES.

We thought she was doing good -- very dry (and a little calmer?) yesterday -- then leaked BAD this evening, on my husband's side of the bed, unfortunately.  She was on a waterproof pad, but it leaked off the edge, or something so it became a bit more of a crisis than it really was (for him, not for me).

Anyway - any tips on the transition from Proin to DES?  Should we refill our Proin one more time, just to have it on hand while she moves over?  

Thanks!

Cara

 

sorry that I'm late to this ... been out of town. 

Did you ever try increasing the dosage of Proin? DES works well for some bitches, but does not work for all of them. 

Cara.M's picture
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We were pretty much at the max. dosage that our vet was comfortable with, on the Proin.  It seems like DES is not going to work on its own -- she has more frequent, albeit smaller, accidents taking 1mg every 3 days.  We could go to every 2 day, maybe?

Vet seems a bit unfamiliar with DES, though her partner recommended it.  I asked about coming the two, and she seemed to not be aware of this possibility, but said maybe we could try combining the 1mg DES every days with 1/2 proin 2x every day (a little less than half her previous dosage).

I would love to hear if anyone with this problem has explored collagen injections.

I don't know that anyone here would have tried that. I do know that there are some Doberman health forums on facebook - so you might try looking there. 

Joined: 2012-10-28

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Is cornsilk an actual treatment for urine incontinence or is it just a wives tail?

Bella who is 7 has urine incontinence once every few months. It is usually linked to over drinking. She has made some big puddles! It helps to take the water bowl away early in the evening, for us, but it hppens so infrequently, we do not do that all the time.

Cara.M's picture
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We did try cornsilk - in our case, it seemed to increase the problem, unfortunately.  The DES, over time, seems to have made something of a difference.  She still has accidents, but they're smaller.